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MDCAT
Biology
2025

Biology · Cell Structure and Function

Work through this past-paper style MCQ, then read the full explanation. Practice more biology questions on mMCQ with adaptive drills and topic analytics.

Question

Which organelle gives rise to primary lysosomes through budding in eukaryotic cells?

Options
  • A

    Smooth endoplasmic reticulum (SER)

  • B

    Rough endoplasmic reticulum (RER)

  • C

    Plasma membrane

  • D

    Golgi cisternae

Explanation

The correct answer is Golgi cisternae. In eukaryotic cells, primary lysosomes are formed from the Golgi apparatus, specifically from its cisternae through a process called budding. The Golgi apparatus modifies and packages enzymes that will become part of the lysosomes.

Other options are incorrect for the following reasons: The Smooth endoplasmic reticulum (SER) is mainly involved in lipid synthesis and does not form lysosomes. The Rough endoplasmic reticulum (RER) synthesizes proteins but does not produce lysosomes itself; it prepares proteins to be sent to the Golgi apparatus instead. The Plasma membrane acts as a barrier and does not participate in lysosome formation.

The smooth endoplasmic reticulum is primarily involved in lipid synthesis and detoxification processes, but it does not play a direct role in the formation of lysosomes.

The rough endoplasmic reticulum is involved in the synthesis of proteins destined for secretion or for lysosomes, but it does not directly contribute to the formation of primary lysosomes.

The plasma membrane serves as the boundary of the cell and is not involved in the production of lysosomes.

The Golgi cisternae are responsible for modifying, sorting, and packaging proteins and lipids, and they give rise to primary lysosomes through the budding process.

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Tagged under Biology · Cell Structure and Function · 2025