Biology · Transport
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Which of the following is true about bradykinin?
- A
It is produced at the site of tissue injury.
- B
It has no role in the leakage of fluids into the tissues in inflammation.
- C
It destroys phagocytes.
- D
It produces interferon gamma.
Bradykinin is a peptide hormone that plays a key role in the inflammatory response. It is produced at the site of tissue injury, where it is generated from kininogen by the action of kallikrein. Bradykinin then binds to specific receptors on blood vessels and other cells, leading to:
- Increased vascular permeability (leakage of fluids into tissues)
- Smooth muscle contraction
- Pain transmission
- Inflammation
Bradykinin is a peptide hormone that plays a key role in the inflammatory response. It is produced at the site of tissue injury, where it is generated from kininogen by the action of kallikrein. Bradykinin then binds to specific receptors on blood vessels and other cells, leading to:
- Increased vascular permeability (leakage of fluids into tissues)
- Smooth muscle contraction
- Pain transmission
- Inflammation
This is incorrect, as bradykinin is a key mediator of increased vascular permeability and fluid leakage.
Bradykinin does not destroy phagocytes, which are important immune cells that engulf and remove pathogens and debris.
Bradykinin does not produce interferon gamma, which is a cytokine involved in immune responses, particularly against viral infections.
Tagged under Biology · Transport · 2023