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MDCAT
Biology
2013

Biology · Transport

Work through this past-paper style MCQ, then read the full explanation. Practice more biology questions on mMCQ with adaptive practice and topic analytics.

Question

Two identical light chains and two identical heavy chains in the antibody molecule are linked by:

Options
  • A

    Disulphide bridges 

  • B

    Peptide bond

  • C

    Glycerol bond

  • D

    Ionic bond 

Explanation

Disulphide bonds can be used to hold different sub-units of protein complexes together, as is found in antibodies between the light chains and between the heavy chains.

The two identical light chains and two identical heavy chains in an antibody molecule are linked by covalent disulfide bridges between cysteine residues.

Peptide bonds are covalent bonds formed between the amino group of one amino acid and the carboxyl group of another amino acid. Peptide bonds are responsible for linking amino acids together to form proteins. However, in antibodies, the heavy chains and light chains are not linked by peptide bonds.

Glycerol is a molecule that is part of triglycerides and phospholipids. It is not involved in linking the heavy and light chains of antibodies.

Ionic bonds are formed by the electrostatic attraction between positively and negatively charged ions. Antibodies do not have ionic bonds between their heavy and light chains.

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Tagged under Biology · Transport · 2013