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MDCAT
Biology
2012

Biology · Cell Cycle

Work through this past-paper style MCQ, then read the full explanation. Practice more biology questions on mMCQ with adaptive practice and topic analytics.

Question

If a person has 44 autosomes + XXY, he will suffer from:

Options
  • A

    Klinefelter’s syndrome 

  • B

    Down’s syndrome 

  • C

    Turner’s syndrome 

  • D

    Edward’s syndrome 

Explanation

The correct answer is Klinefelter's syndrome. Klinefelter's syndrome is characterized by the presence of an additional X chromosome in males, resulting in a karyotype of 47,XXY. This condition can lead to various physical, hormonal, and developmental differences in affected individuals. 

It is a genetic disorder which occur in male when he has one extra X chromosome, as a result, it's body condition changes and growth of body also changes.

Down's syndrome, also known as Trisomy 21, is a genetic disorder caused by the presence of an extra chromosome 21. It typically leads to intellectual disabilities and distinctive physical features. 

These affected individuals have one missing X chromosome with only 45 chromosomes (44 autosomes + X). Individuals with this condition often do not survive pregnancy and are aborted. Those who survive have female appearance with short stature, webbed neck, without ovaries and complete absence of germ cells.

Edward's syndrome, also known as trisomy 18, is caused by an extra copy of chromosome 18 (resulting in a total of 47 chromosomes). This condition is associated with severe developmental and physical abnormalities, and individuals with Edward's syndrome often have a short lifespan. 

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Tagged under Biology · Cell Cycle · 2012