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MDCAT
Biology
2012

Biology · Support and Movement

Work through this past-paper style MCQ, then read the full explanation. Practice more biology questions on mMCQ with adaptive practice and topic analytics.

Question

When calcium ions are released from the sarcoplasmic reticulum, they bind with ________ during muscle contraction. 

Options
  • A

    Tropomyosin 

  • B

    Sarcolemma 

  • C

    Cytosol’s ions 

  • D

    Troponin 

Explanation

Calcium ions, which are released, bind to troponin, which in turn allows the tropomyosin to give way, thus allowing the muscle to stay contracted.

Tropomyosin is a protein that is involved in regulating muscle contraction. It covers the binding sites on actin molecules in a resting muscle, preventing myosin heads from attaching to actin. 

The sarcolemma is the plasma membrane of a muscle cell (muscle fiber). It is responsible for maintaining the integrity of the muscle cell and controlling the movement of ions in and out of the cell. 

This option refers to ions present in the cytosol, the fluid inside a cell. While ions play various roles in cellular processes, they are not directly involved in the binding of calcium ions during muscle contraction.

Troponin is a protein complex that plays a crucial role in muscle contraction. When calcium ions are released from the sarcoplasmic reticulum, they bind to troponin. This binding causes a conformational change in troponin, which leads to the movement of tropomyosin away from the binding sites on actin, allowing myosin heads to attach and initiate muscle contraction. 

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Tagged under Biology · Support and Movement · 2012