A Levels Biology (9700)•9700/12/O/N/24

Explanation
CO2 Transport in Blood and Hemoglobin Interactions
Steps:
- Recall that CO2 is transported in blood as dissolved gas, bicarbonate ions, and carbaminohemoglobin.
- Evaluate each statement against known physiological processes: CO2 binding to hemoglobin, enzyme roles, and gas exchange.
- Identify the statement accurately describing carbonic anhydrase's function in catalyzing CO2 hydration.
- Confirm B as correct by verifying it matches the enzyme's role in forming carbonic acid.
Why B is correct:
- Carbonic anhydrase catalyzes the reaction CO2 + H2O ⇌ H2CO3 (carbonic acid), speeding up bicarbonate formation for CO2 transport.
Why the others are wrong:
- A: CO2 combines with hemoglobin's amino groups, not directly with hemoglobin itself, to form carbaminohaemoglobin.
- C: At lungs, CO2 is released as bicarbonate converts to CO2 via the reverse reaction, not carbonic acid and water reacting.
- D: Higher CO2 concentration decreases hemoglobin's oxygen affinity (Bohr effect), not increases it.
Final answer: B
Topic: Transport of oxygen and carbon dioxide
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