A Levels Biology (9700)•9700/13/O/N/23

Explanation
Mature RBCs Perform Membrane Functions but Lack Nucleus and Organelles
Steps:
- Mature red blood cells (RBCs) eject their nucleus and organelles during maturation to maximize space for hemoglobin.
- Active transport relies on plasma membrane pumps like Na+/K+ ATPase, which RBCs retain for ion balance.
- Cell division, phagocytosis, and protein synthesis require nuclear DNA, ribosomes, or cytoskeletal elements absent in mature RBCs.
- Thus, only active transport is feasible without these structures.
Why A is correct:
- Active transport uses ATP-driven membrane proteins for ion gradients, a function preserved in anucleate RBCs to maintain shape and flexibility.
Why the others are wrong:
- B: Cell division needs nuclear DNA replication and mitosis machinery, impossible without a nucleus.
- C: Phagocytosis requires actin cytoskeleton and lysosomes for engulfing particles, both absent in RBCs.
- D: Protein synthesis demands ribosomes and mRNA from a nucleus, which mature RBCs lack.
Final answer: A
Topic: Movement into and out of cells
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