A Levels Biology (9700)•9700/13/O/N/22

Explanation
Starling's Forces and Edema Steps:
- Fluid exchange follows Starling's equation: net filtration = (capillary hydrostatic - interstitial hydrostatic) - (plasma oncotic - interstitial oncotic).
- Increased net filtration causes more fluid to leave capillaries and accumulate in tissues, leading to edema.
- Evaluate options by their impact on oncotic pressures, which oppose filtration.
- Higher interstitial oncotic pressure reduces the gradient pulling fluid back into capillaries, increasing tissue fluid.
Why C is correct:
- Higher tissue protein concentration elevates interstitial oncotic pressure, decreasing (plasma oncotic - interstitial oncotic) in Starling's equation, which increases net filtration and tissue fluid accumulation.
Why the others are wrong:
- A: Lower blood pressure decreases capillary hydrostatic pressure, reducing net filtration and tissue fluid.
- B: Higher blood plasma protein concentration raises plasma oncotic pressure, increasing fluid reabsorption into capillaries.
- D: Lower tissue fluid protein concentration reduces interstitial oncotic pressure, enhancing the gradient for fluid reabsorption.
Final answer: C
Topic: The circulatory system
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