A Levels Biology (9700)•9700/11/O/N/22

Explanation
Nucleus as the site of rRNA synthesis
Steps:
- Recall that the nucleus houses genetic material and controls cellular activities.
- Identify key nuclear components: chromatin for DNA, nucleolus for ribosome biogenesis.
- Link function to rRNA: nucleolus transcribes rRNA from DNA templates.
- Eliminate options by matching to known cellular processes outside the nucleus.
Why D is correct:
- The nucleolus in the nucleus synthesizes rRNA, essential for ribosome assembly, as per eukaryotic cell biology definitions.
Why the others are wrong:
- A: Nuclear envelope forms and breaks down during mitosis, not a primary nucleus function.
- B: Rough ER forms in the cytoplasm, attached to ER membranes, not the nucleus.
- C: Ribosomal proteins synthesize on cytoplasmic ribosomes, not in the nucleus.
Final answer: D
Topic: Protein synthesis
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