Bohr Effect Shifts Oxygen Dissociation Curve

Steps:

• Hemoglobin binds oxygen based on partial pressure and environmental factors like CO2.
• Increasing CO2 lowers blood pH, triggering the Bohr effect.
• This shifts the oxygen-hemoglobin dissociation curve rightward, reducing oxygen affinity.
• Result: harder for hemoglobin to bind oxygen in lungs, easier to release in tissues.

Why B is correct:

• Bohr effect decreases hemoglobin's oxygen affinity, impairing uptake at lungs' pO2 but enhancing release at tissues' lower pO2.

Why the others are wrong:

• A: Increasing CO2 improves oxygen release efficiency, not decreases it.
• C: Increasing CO2 reduces uptake efficiency, not increases it.
• D: Increasing CO2 reduces uptake efficiency, not increases it.

Final answer: B