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A Levels Biology (9700)•9700/12/O/N/21
Question 21 from 9700/12/O/N/21

Explanation

Tumor cells accelerate division by shortening interphase

Steps:

  • Cell cycle consists of interphase (G1, S, G2) and M phase (mitosis + cytokinesis).
  • Tumor formation requires rapid proliferation, shortening overall cycle time.
  • Checkpoints in interphase regulate progression; cancer cells bypass these for faster cycling.
  • Interphase, the longest phase, is primarily shortened to enable quick DNA replication and growth.

Why B is correct:

  • Interphase is shortened in tumors as cells reduce G1 duration, allowing unchecked progression per the cell cycle control model.

Why the others are wrong:

  • A: Cytokinesis divides cytoplasm post-mitosis and remains brief, unaffected by tumor acceleration.
  • C: Mitosis duration stays similar or lengthens slightly in tumors due to error-prone division.
  • D: Telophase, a mitosis subphase, is not specifically shortened in tumor cells.

Final answer: B

Topic: Replication and division of nuclei and cells

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