A Levels Biology (9700)•9700/12/O/N/21

Explanation
Tumor cells accelerate division by shortening interphase
Steps:
- Cell cycle consists of interphase (G1, S, G2) and M phase (mitosis + cytokinesis).
- Tumor formation requires rapid proliferation, shortening overall cycle time.
- Checkpoints in interphase regulate progression; cancer cells bypass these for faster cycling.
- Interphase, the longest phase, is primarily shortened to enable quick DNA replication and growth.
Why B is correct:
- Interphase is shortened in tumors as cells reduce G1 duration, allowing unchecked progression per the cell cycle control model.
Why the others are wrong:
- A: Cytokinesis divides cytoplasm post-mitosis and remains brief, unaffected by tumor acceleration.
- C: Mitosis duration stays similar or lengthens slightly in tumors due to error-prone division.
- D: Telophase, a mitosis subphase, is not specifically shortened in tumor cells.
Final answer: B
Topic: Replication and division of nuclei and cells
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