Disease identification via zoonosis, blood transmission, and drug resistance

Steps:

• Match zoonotic transmission: Disease spreads from animals to humans and animals.
• Confirm blood transfusion as a transmission mode: Involves contaminated blood transfer.
• Verify multiple drug resistance: Majority of human cases exhibit resistance to multiple drugs.
• Compare features against options to find the best fit.

Why C is correct:

• Malaria is zoonotic (e.g., Plasmodium knowlesi from monkeys to humans), transmits via contaminated blood transfusions, and multiple drug-resistant strains (e.g., to chloroquine, artemisinin) affect the majority of cases globally, per WHO definitions of resistance.

Why the others are wrong:

• A. Cholera: Waterborne bacterial infection, not zoonotic or blood-transmitted.
• B. HIV/AIDS: Zoonotic and blood-transmitted, but viral with antiretroviral resistance, not "multiple drug resistance" in majority cases.
• D. Tuberculosis: Zoonotic (e.g., bovine TB), but primarily airborne, not via blood transfusion.

Final answer: C