A Levels Biology (9700)•9700/11/O/N/21

Explanation
Mitotic inhibitors target proliferating cells, impacting regeneration and growth
Steps:
- The drug kills cells in mitosis, blocking cell division in proliferative tissues.
- Stem cells (3) rely on mitosis for self-renewal, so their numbers decline.
- Tissue repair (4) depends on mitotic proliferation to replace damaged cells.
- Tumour formation (5) requires uncontrolled mitosis for cancer cell expansion.
- Cell repair (1) and replacement (2) involve non-proliferative maintenance or differentiation, unaffected directly.
Why D is correct:
- It selects processes tied to mitosis: stem cell division maintains populations, tissue repair needs new cells via mitosis, and tumours grow through mitotic proliferation (per cell cycle biology).
Why the others are wrong:
- A includes 1 and 2, which do not depend on mitosis.
- B includes 1 and 2 but omits mitosis-reliant 4 and 5.
- C includes 2 but excludes stem cell impact (3).
Final answer: D
Topic: Replication and division of nuclei and cells
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