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A Levels Biology (9700)•9700/11/O/N/21
Question 14 from 9700/11/O/N/21

Explanation

Ligand-Receptor Binding in Cell Signaling

Steps:

  • Signal molecules, or ligands, travel to target cells and interact with their surface.
  • Detection occurs when the ligand fits specifically into a receptor protein on the cell membrane.
  • This binding triggers intracellular responses, like enzyme activation or ion channel opening.
  • Specificity ensures only target cells respond, based on complementary molecular shapes.

Why A is correct:

  • Receptors act as locks, and signal molecules as keys with complementary shapes, enabling specific recognition per the lock-and-key model in biochemistry.

Why the others are wrong:

  • B: Diffusion explains molecule transport, not detection by the target cell.
  • C: Endocytosis internalizes some signals but is not the primary detection mechanism.
  • D: Binding is specific to matching receptor types, not any receptor.

Final answer: A

Topic: Fluid mosaic membranes

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