Bohr Effect on Hemoglobin-Oxygen Affinity

Steps:

• Hemoglobin's oxygen binding is influenced by CO2 via the Bohr effect.
• Decreasing CO2 reduces acidity, shifting the oxygen dissociation curve leftward.
• Left shift increases hemoglobin's affinity for oxygen.
• Higher affinity enhances oxygen uptake in lungs but impairs release in tissues.

Why C is correct:

• The Bohr effect defines that low CO2 increases hemoglobin's oxygen affinity, promoting uptake (more efficient) while reducing release (less efficient) to match low-CO2 lung conditions.

Why the others are wrong:

• A: Decreasing CO2 boosts uptake efficiency, not reduces it.
• B: Low CO2 hinders release, not enhances it (opposite of high-CO2 effect).
• D: Affinity increase cannot improve both uptake and release simultaneously.

Final answer: C