A Levels Biology (9700)•9700/11/O/N/20

Explanation
Telomeres double per chromosome in daughter nuclei during telophase
Steps:
- Diploid cell has 22 chromosomes total (2n=22), replicated to 44 chromatids during mitosis.
- In telophase, chromosomes separate to poles, forming two nuclei each with 22 chromosomes.
- Staining targets one nucleus, which contains 22 decondensed chromosomes.
- Each chromosome has two telomeres (one per end), so 22 × 2 = 44 telomeres observed.
Why B is correct:
- Linear eukaryotic chromosomes have two telomeres by definition, one at each terminus, yielding 44 for 22 chromosomes.
Why the others are wrong:
- A. Counts chromosomes instead of telomeres per chromosome.
- C. Overcounts by adding extra, possibly confusing with total chromatids or pairs.
- D. Doubles for both nuclei, but question specifies one nucleus.
Final answer: B
Topic: Chromosome behaviour in mitosis
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