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A Levels Biology (9700)•9700/13/O/N/18
Question 37 from 9700/13/O/N/18

Explanation

Non-specific immune benefits of measles vaccine

Steps:

  • Identify that the vaccine provides protection beyond measles, indicating non-specific effects on immunity.
  • Recall vaccines primarily activate adaptive immunity via B and T cells, but measles vaccine boosts innate responses against other infections.
  • Eliminate options claiming specific memory or passive/natural immunity to unrelated pathogens, as these are antigen-specific.
  • Select the option linking vaccine-induced cells to broader antibody effects.

Why B is correct:

  • Memory cells differentiate into plasma cells that produce antibodies; in this context, anti-measles antibodies provide cross-protection by binding non-specifically to other pathogens, enhancing overall survival per immunological studies on vaccine heterologous effects.

Why the others are wrong:

  • A: B-cell memory provides specific active immunity, not passive, and is measles-targeted, not broadly protective.
  • C: Identical to B but incomplete; lacks explanation of cross-binding for extra protection.
  • D: T-cell memory confers specific adaptive immunity, not "natural" (innate) against unrelated infections.

Final answer: B

Topic: Antibodies and vaccination

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