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A Levels Biology (9700)•9700/11/O/N/18
Question 15 from 9700/11/O/N/18

Explanation

Glycoproteins as cell surface antigens with internal hydrophobic domains

Steps:

  • Identify glycoprotein function: serves as antigen for immune recognition via extracellular carbohydrate chains.
  • Examine structure: membrane glycoproteins have hydrophilic exterior for antigen display and hydrophobic interior regions for membrane anchoring.
  • Analyze regions P and Q: labeled with hydrophobic R groups, indicating transmembrane or cytoplasmic domains.
  • Match to choices: antigen role fits, with hydrophobic groups in cytoplasm for stability.

Why A is correct:

  • Glycoproteins function as antigens by exposing unique oligosaccharides outside the cell, while hydrophobic R groups in transmembrane/cytoplasmic regions anchor the molecule per membrane protein topology.

Why the others are wrong:

  • B: Carriers transport ions/molecules across membranes, not primarily immune identifiers.
  • C: Channels form pores for passage, with hydrophobic regions in membrane but hydrophilic lining outside.
  • D: Receptors bind extracellular signals, placing hydrophobic R groups in cytoplasm but mismatching antigen role.

Final answer: A

Topic: Fluid mosaic membranes

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