A Levels Biology (9700)•9700/13/M/J/25

Explanation
Ribosomal RNA locations in eukaryotic cells
Steps:
- Identify structures typically labeled as 1 (ribosomes), 2 (nucleolus), and 3 (rough endoplasmic reticulum) in cell diagrams.
- Recall rRNA is a key component of ribosomes, which are free in cytoplasm or attached to rough ER.
- Note rRNA is synthesized and assembled into ribosomal subunits in the nucleolus within the nucleus.
- Confirm all three structures associate with or contain rRNA during synthesis, assembly, or function.
Why A is correct:
- rRNA is present in ribosomes (structure 1), nucleolus (structure 2 for synthesis), and rough ER (structure 3 via attached ribosomes), per standard cell biology definitions.
Why the others are wrong:
- B excludes 3, but rough ER contains rRNA-bound ribosomes for protein synthesis.
- C excludes 1, but ribosomes are the primary site of rRNA function.
- D excludes 1 and 2, ignoring rRNA's core role in ribosomes and nucleolar assembly.
Final answer: A
Topic: Protein synthesis
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