A Levels Biology (9700)•9700/12/M/J/25

Explanation
Telomeres cap both ends of each chromatid in G2 interphase
Steps:
- Human body cells in interphase (G2 phase) have 46 chromosomes, each consisting of 2 sister chromatids, for a total of 92 chromatids.
- Telomeres are repetitive DNA sequences that protect the ends of linear chromosomes.
- Each chromatid is a linear DNA molecule with two distinct ends.
- Multiply chromatids by telomeres per chromatid: 92 × 2 = 184 telomeres.
Why D is correct:
- Each of the 92 chromatids in G2 interphase has telomeres at both ends, per the definition of telomeres as caps on linear DNA molecules.
Why the others are wrong:
- A: Underestimates by assuming one telomere per chromosome, ignoring two ends and two chromatids per chromosome.
- B: Counts two telomeres per chromosome but overlooks that sister chromatids each have their own two telomeres.
- C: Assumes one telomere per chromatid, but each chromatid requires two for both ends.
Final answer: D
Topic: Replication and division of nuclei and cells
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