A Levels Biology (9700)•9700/11/M/J/25

Explanation
Enzyme Active Site and Induced Fit Model
Steps:
- Statement 1 is correct: Enzymes possess an active site, a specific surface region where the substrate binds via complementary shapes.
- Statement 2 is correct: In the induced fit model, both enzyme and substrate undergo slight, temporary shape changes to optimize binding and catalysis.
- Statement 3 is incorrect: Enzymes do not permanently change shape; they revert to their original conformation after the reaction, releasing products.
- Therefore, only statements 1 and 2 accurately describe enzyme action, selecting option B.
Why B is correct:
- Aligns with the lock-and-key and induced fit models, where active site binding (1) and reversible shape adjustments (2) enable catalysis without permanent alteration.
Why the others are wrong:
- A includes 3, but permanent shape change violates enzyme reusability.
- C excludes 1, yet active sites are fundamental to all enzyme function.
- D selects only 3, which misrepresents the temporary nature of enzyme-substrate interactions.
Final answer: B
Topic: Mode of action of enzymes
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