Hybridoma method fuses lymphocytes with myeloma cells

Steps:

• Identify hybridoma as technique for monoclonal antibody production.
• Recall process: isolate antigen-specific B lymphocytes from immune animal.
• Fuse these lymphocytes with immortal myeloma cells.
• Select hybridomas producing desired antibodies.

Why C is correct:

• Lymphocytes (B cells) are antibody-secreting cells providing specificity in hybridoma fusion.

Why the others are wrong:

• A. Antigens: stimulate immune response but are not fused in the method.
• B. Clones: refer to resulting hybridoma cell lines, not initial components.
• D. Myeloma cells: provide immortality but are fused with lymphocytes, not the blank.

Final answer: C