A Levels Biology (9700)•9700/13/M/J/23

Explanation
Asymmetric distribution of membrane components
Steps:
- Identify cholesterol's position: it intercalates between phospholipid molecules in the hydrophobic core of the bilayer.
- Locate carbohydrate chains of glycolipids: they extend mainly from the outer (extracellular) leaflet.
- Locate carbohydrate chains of glycoproteins: they also project mainly from the outer surface for cell recognition.
- Match to options: only D aligns with bilayer embedding for cholesterol and outer asymmetry for both carbs.
Why D is correct:
- In the fluid mosaic model, cholesterol stabilizes the bilayer by inserting between phospholipids, while glycolipid and glycoprotein carbs are asymmetrically placed on the extracellular side for functions like signaling.
Why the others are wrong:
- A: Misplaces cholesterol between heads (not the core) and inverts carb positions to inner/outer.
- B: Positions cholesterol wrongly between heads and swaps carb asymmetries.
- C: Correctly places cholesterol but wrongly assigns both carbs to inner surface, ignoring extracellular orientation.
Final answer: D
Topic: Fluid mosaic membranes
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