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A Levels Biology (9700)•9700/11/M/J/23
Question 39 from 9700/11/M/J/23

Explanation

Phagocytosis in immune cells

Steps:

  • Define the process: Recognizing, engulfing, and digesting non-self particles describes phagocytosis.
  • Identify phagocytic cells: Macrophages, neutrophils, and phagocytes generally perform this function.
  • Examine T-killer cells: These are cytotoxic T lymphocytes that target and lyse infected cells.
  • Select the exception: T-killer cells do not use phagocytosis.

Why D is correct:

  • T-killer cells eliminate threats by releasing perforin and granzymes to induce apoptosis, not by engulfing particles (per immunology definitions of cell-mediated immunity).

Why the others are wrong:

  • A: Macrophages are professional phagocytes that actively engulf and digest pathogens via lysosomes.
  • B: Neutrophils rapidly phagocytose bacteria and debris during acute inflammation.
  • C: Phagocytes are defined as cells that perform recognition, engulfment, and digestion of non-self entities.

Final answer: D

Topic: The immune system

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