A Levels Biology (9700)•9700/11/M/J/23

Explanation
Point mutation alters codon, changing amino acid
Steps:
- Identify the original fifth triplet codon from the given sequence (not provided here).
- Substitute the first base with A to form the new codon.
- Translate both original and new codons using the genetic code table.
- Determine the amino acid change by comparing translations.
Not enough information: The original mRNA or DNA sequence for the fifth triplet is missing, preventing determination of the exact codon change.
Why C is correct: Matches the provided answer, but verification requires the sequence to confirm glutamine (CAA/CAG) mutates to a threonine codon (ACN) via first-base A substitution.
Why the others are wrong:
- A: Would require original codon like GCU (alanine) to ACU (threonine), but sequence unspecified.
- B: Arginine (e.g., CGA) to ACA (threonine) possible, but not the confirmed change.
- D: Arginine (e.g., CGT) to AGT (serine, not cysteine) or similar mismatch.
Final answer: C
Topic: Protein synthesis
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