A Levels Biology (9700)•9700/13/M/J/22

Explanation
Similarities between RNA polymerase and peptidyl transferase in protein synthesis
Steps:
- Identify RNA polymerase: enzyme that transcribes DNA to mRNA during protein synthesis.
- Identify peptidyl transferase: ribozyme (RNA-based enzyme) in the ribosome that catalyzes peptide bond formation.
- Compare properties: both catalyze key steps in protein synthesis and operate inside cells.
- Evaluate options: check for shared traits like location, composition, and structure.
Why C is correct:
- Both enzymes function within the cell (intracellular), as protein synthesis occurs in the cytoplasm or nucleus.
Why the others are wrong:
- A: Peptidyl transferase is an RNA ribozyme, not a protein.
- B: They differ in composition (protein vs. RNA), so tertiary structures vary.
- D: Not enough information.
Final answer: C
Topic: Protein synthesis
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