A Levels Biology (9700)•9700/12/M/J/22

Explanation
DNA doubles in S phase and stays doubled in G2
Steps:
- G1 phase: Cell has 1.2 × 10^9 g DNA (2C content, unreplicated diploid genome).
- S phase: DNA replication synthesizes exact copy of each chromosome, doubling mass to 2.4 × 10^9 g (4C content).
- End of S phase: DNA mass is 2.4 × 10^9 g.
- G2 phase: Cell prepares for mitosis with no additional replication; DNA mass remains 2.4 × 10^9 g.
Why D is correct:
- Cell cycle definition: S phase transitions DNA from 2C to 4C via semiconservative replication; G2 maintains 4C until mitosis.
Why the others are wrong:
- A: End of S phase must double DNA mass, not remain at G1 level.
- B: Identical to D, but listed separately; still correct, though question specifies D.
- C: DNA does not decrease in G2; it stays doubled post-S phase.
Final answer: D
Topic: Replication and division of nuclei and cells
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