A Levels Biology (9700)•9700/11/M/J/22

Explanation
ABO Blood Type Compatibility for Recipients
Steps:
- AB blood type contains A and B antigens but lacks anti-A and anti-B antibodies.
- Recipient antibodies must not react with donor red blood cell antigens to prevent agglutination.
- Donor AB provides matching antigens with no reaction due to absent antibodies in recipient.
- Donor O lacks A and B antigens, making it universally safe as no targets for reaction.
Why D is correct:
- ABO system rules state AB recipients accept AB (exact match, no clumping) and O (no antigens to trigger immune response).
Why the others are wrong:
- A. O only: Excludes AB, the fully matched type essential for optimal transfusion.
- B. A and B only: Excludes AB and O; A/B donor plasma antibodies can react with recipient antigens in whole blood.
- C. A, B and O: Excludes AB, ignoring the primary compatible donor for AB recipients.
Final answer: D
Topic: Antibodies and vaccination
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