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A Levels Biology (9700)•9700/11/M/J/22
Question 14 from 9700/11/M/J/22

Explanation

Liposome Drug Transport Properties

Steps:

  • Liposomes have an aqueous core (hydrophilic) and a phospholipid bilayer (hydrophobic).
  • Hydrophilic drugs dissolve in water-based regions like the core.
  • Hydrophobic drugs integrate into lipid regions like the bilayer.
  • Match drug properties to labeled sections: core for hydrophilic, bilayer for hydrophobic.

Why C is correct:

  • C matches hydrophilic drugs to the aqueous core (location 1) and hydrophobic drugs to the bilayer (location 2), aligning with liposome structure where polar substances stay in water compartments and nonpolar in lipid layers.

Why the others are wrong:

  • A reverses the properties, placing hydrophobic drugs in the hydrophilic core, which prevents solubility.
  • B swaps them entirely, mismatching both locations to liposome regions.
  • D incorrectly suggests both locations suit only one property type, ignoring compartment differences.

Final answer: C

Topic: Movement into and out of cells

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