A Levels Biology (9700)•9700/12/M/J/21

Explanation
Cross-protection via antibody cross-reactivity
Steps:
- The measles vaccine triggers adaptive immunity, producing memory cells for long-term protection.
- This immunity extends to other infections through non-specific or cross-reactive mechanisms.
- Evaluate options: focus on how memory cells contribute to broader defense without direct exposure.
- Select the choice describing antibody-mediated binding to unrelated pathogens.
Why B is correct:
- Memory cells differentiate into plasma cells that produce anti-measles antibodies capable of cross-reacting and binding to similar epitopes on other pathogens, providing heterologous immunity as per immunological cross-protection principles.
Why the others are wrong:
- A: Memory B-lymphocytes confer active, not passive, immunity; passive immunity is temporary and maternally derived or injected.
- C: Incomplete description lacks specificity on antibody binding to other infections, failing to explain cross-protection.
- D: Vaccines induce artificial active immunity, not natural (from prior infection); T-lymphocytes primarily handle cellular responses, not broad antibody-based protection.
Final answer: B
Topic: Antibodies and vaccination
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