Specificity of Monoclonal Antibodies to Cancer Antigens

Steps:

• Identify that monoclonal antibodies are produced to target specific antigens.
• Recognize cancer cells express unique tumor-specific antigens not found on normal cells.
• Understand these antibodies bind selectively to cancer cell antigens, enabling targeted therapy.
• Confirm this specificity allows precise delivery of treatments without harming healthy cells.

Why A is correct:

• Cancer cells display distinct tumor antigens, allowing monoclonal antibodies to bind specifically as per their definition of recognizing unique epitopes.

Why the others are wrong:

• B: Attaching drugs is a method of use, not the reason for targeting cancer cells.
• C: Cancer cells do not secrete antigens; they express them on their surface for antibody binding.
• D: Hybridomas produce monoclonal antibodies from B-cells and myeloma cells, not cancer cells directly.

Final answer: A