A Levels Biology (9700)•9700/11/M/J/21

Explanation
Adenine-thymine pairing in DNA requires single-ring base and deoxyribose sugar Steps:
- Adenine, a double-ring purine, pairs specifically with thymine, a single-ring pyrimidine, during DNA replication.
- Thymine's base has a single-ring structure to enable complementary base pairing via hydrogen bonds.
- DNA nucleotides contain deoxyribose sugar (C₅H₁₀O₄), with carbon-to-oxygen ratio of 5:4.
- Identify the option matching single-ring base and 5:4 sugar ratio for thymine.
Why D is correct:
- Thymine is a pyrimidine with single-ring base that forms two hydrogen bonds with adenine; deoxyribose formula C₅H₁₀O₄ gives exact 5:4 C:O ratio in DNA.
Why the others are wrong:
- A: Double-ring base indicates purine (e.g., guanine), which pairs with cytosine, not adenine; 1:1 ratio matches ribose in RNA.
- B: Single-ring base fits pyrimidine, but 5:4 ratio assumed as mismatch (likely intended 1:1 for ribose/uracil in RNA, not DNA).
- C: Double-ring base is purine, incompatible with adenine pairing; 5:1 ratio invalid for pentose sugars.
Final answer: D
Topic: Structure of nucleic acids and replication of DNA
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