A Levels Biology (9700)•9700/13/M/J/20

Explanation
Effects of cigarette smoke components on the body
Steps:
- Identify carbon monoxide's action: binds to hemoglobin, forming carboxyhemoglobin and reducing oxygen delivery.
- Identify nicotine's action: acts as a stimulant, exciting nerve endings and increasing heart rate.
- Identify tar's action: contains carcinogens that damage lung tissue and promote cancer.
- Compare options to these known effects to select the matching one.
Why D is correct:
- Matches definitions: carbon monoxide competes with oxygen for hemoglobin binding sites (per gas physiology); nicotine mimics acetylcholine to stimulate nicotinic receptors on nerve endings; tar includes polycyclic aromatic hydrocarbons, known carcinogens per toxicology.
Why the others are wrong:
- A: Carbon monoxide does not stimulate nerves; nicotine narrows bronchi, not arteries; tar causes emphysema, not directly obstructive disease.
- B: Nicotine does not increase clots; tar does not block goblet cells, which produce mucus.
- C: Carbon monoxide does not raise blood pressure; nicotine does not bind hemoglobin; tar does not increase clot risk.
Final answer: D
Topic: The gas exchange system
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