A Levels Biology (9700)•9700/13/M/J/20

Explanation
DNA Replication Statement Accuracy
Steps:
- Statement 1 is correct: DNA replication occurs in stages (initiation, elongation, termination) and follows semi-conservative replication where each strand templates the new opposite strand.
- Statement 2 is incorrect: DNA polymerase links nucleotides via phosphodiester bonds, not bases directly, as bases are components of nucleotides.
- Statement 3 is correct: Helicase breaks hydrogen bonds between A-T and C-G base pairs to unwind and separate DNA strands for replication.
- Only statements 1 and 3 are accurate, matching option C.
Why C is correct:
- DNA replication requires template-guided synthesis (semi-conservative model) and hydrogen bond breakage for strand separation, as defined in molecular biology.
Why the others are wrong:
- A includes incorrect statement 2 on polymerase function.
- B includes incorrect statement 2 and omits correct statement 3.
- D omits correct statements 1 and 3.
Final answer: C
Topic: Structure of nucleic acids and replication of DNA
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