Lipid targeting prevents easy mutational resistance

Steps:

• Antibiotics binding proteins enable resistance via DNA mutations altering protein structure.
• Teixobactin targets lipids, not proteins, avoiding protein mutation pathways.
• Lipid structures form through biochemical pathways, not direct DNA coding.
• Without DNA-coded targets, random mutations rarely confer resistance to lipid-binding antibiotics.

Why D is correct:

• Statement 3 states lipid structure is not DNA-coded, directly explaining low resistance risk per evolutionary biology, as mutations cannot easily modify non-genetic targets.

Why the others are wrong:

• A includes 1, which describes protein-based resistance mechanism, contradicting unlikelihood for teixobactin.
• B includes 1, which promotes resistance development, not prevention.
• C includes 2, a factual difference but not explanatory without 3's genetic rationale.

Final answer: D