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A Levels Biology (9700)•9700/13/M/J/19
Question 39 from 9700/13/M/J/19

Explanation

Trastuzumab targets cancer cell receptors to halt division

Steps:

  • Growth factors bind to cell surface receptors to trigger division, leading to tumors.
  • Trastuzumab attaches to a specific growth factor receptor on tumor cells.
  • This binding blocks the growth signal, stopping cell division.
  • Such targeted binding matches the function of monoclonal antibodies, which are engineered to recognize and neutralize specific proteins.

Why A is correct:

  • Monoclonal antibodies are lab-produced proteins that mimic immune responses by binding precisely to targets like HER2 receptors, as defined in immunology and oncology.

Why the others are wrong:

  • B: Antibiotics kill bacteria by disrupting cell walls or protein synthesis, unrelated to receptor binding in cancer.
  • C: Option is incomplete and provides no viable description.
  • D: Enzyme inhibitors block catalytic sites on enzymes to halt reactions, but trastuzumab acts on surface receptors, not intracellular enzymes.

Final answer: A

Topic: Antibodies and vaccination

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