A Levels Biology (9700)•9700/13/M/J/19

Explanation
Correct distribution of antigens in body fluids
Steps:
- Identify the substance in each option: A (antigen), B (glucose), C (lymphocyte), D (neutrophil).
- Recall locations: blood carries substances systemically; lymph transports immune cells; tissue fluid bathes cells in tissues.
- Match presences: antigens enter via infection sites, appearing in blood and tissue fluid but filtered out of lymph.
- Verify option A matches: ✓ blood, x lymph, ✓ tissue fluid.
Why A is correct:
- Antigens are foreign molecules that provoke immune responses, present in blood (circulation) and tissue fluid (infection sites) but absent in lymph, which mainly carries lymphocytes.
Why the others are wrong:
- B: Glucose, a simple sugar, diffuses into all three fluids for cellular energy supply.
- C: Lymphocytes, key immune cells, circulate in blood and lymph nodes (thus lymph) and migrate to tissue fluid during responses.
- D: Neutrophils, phagocytic white blood cells, reside in blood and enter tissue fluid at infection sites but rarely in lymph.
Final answer: A
Topic: The immune system
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