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A Levels Biology (9700)•9700/12/M/J/19
Question 40 from 9700/12/M/J/19

Explanation

Antibody structural features in diagrams

Steps:

  • Identify key antibody types from diagrams: likely IgG (monomer), IgA (dimer), IgM (pentamer).
  • Match features: IgA dimer has 4 antigen binding sites; IgM pentamer derives from 5 monomer units, each with 2 heavy chains.
  • Evaluate options against standard compositions: 2 heavy (H) and 2 light (L) chains per monomer, with multiples in multimers.
  • Select option aligning with binding sites and chain counts for IgA and IgM.

Why B is correct:

  • Per antibody definition, dimeric IgA features 4 binding sites for antigens, while pentameric IgM incorporates 5 structural units with associated heavy chains, matching the diagram descriptions.

Why the others are wrong:

  • A: IgA and IgM monomers each have 2 light chains, not 1 for 2 units.
  • C: Heavy chains have 1 hinge region per monomer; no antibody has 5 light chains standardly.
  • D: No antibody has 4 hinge regions; IgM has 10 binding sites but option mismatches chain details.

Final answer: B

Topic: Antibodies and vaccination

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