A Levels Biology (9700)•9700/12/M/J/18

Explanation
AV Valve Regurgitation Effects Steps:
- Incomplete AV valve closure causes blood to regurgitate into the atrium during ventricular systole.
- Regurgitant volume increases atrial blood volume, elevating atrial pressure.
- Net forward blood flow from the ventricle decreases due to backward leakage.
- Reduced left ventricular output lowers overall cardiac output, decreasing pulmonary artery inflow.
Why D is correct:
- Mitral regurgitation definition: backward flow raises left atrial pressure (v wave), while reduced stroke volume decreases pulmonary artery blood flow via lower systemic return and cardiac output.
Why the others are wrong:
- A: Oxygenation depends on pulmonary capillary exchange, not immediate volume reduction.
- B: Diastolic LV pressure relates to preload, which may rise from volume overload, not fall.
- C: Systolic LA pressure rises from regurgitant volume, not lowers; forward flow reduction affects aorta, not pulmonary artery as stated.
Final answer: D
Topic: The heart
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