O Levels Biology (5090)•5090/12/O/N/24

Explanation
Carbon monoxide impairs hemoglobin's oxygen-binding capacity
Steps:
- Hemoglobin in red blood cells binds oxygen for transport to organs.
- Carbon monoxide binds to hemoglobin more tightly than oxygen, forming carboxyhemoglobin.
- This blocks oxygen attachment sites on hemoglobin.
- Reduced oxygen delivery starves body's organs of oxygen.
Why B is correct:
- Hemoglobin's primary function is reversible oxygen binding and transport; CO's higher affinity (200–250 times stronger) prevents this per gas physiology laws.
Why the others are wrong:
- A: Clotting involves platelets and fibrinogen, unaffected by CO binding to hemoglobin.
- C: Antibody production by lymphocytes is an immune process, not linked to gas transport.
- D: Adrenaline dissolves in plasma for transport, independent of hemoglobin.
Final answer: B
Topic: Blood
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