O Levels Biology (5090)•5090/11/O/N/24

Explanation
Venous Return and Muscle Pump in Prolonged Sitting
Steps:
- Blood returns to the heart via veins, aided by skeletal muscle contractions that compress veins and push blood upward.
- In veins, one-way valves prevent backflow, but without muscle activity, blood pools in lower extremities.
- Prolonged sitting in aircraft reduces leg muscle contractions, leading to venous stasis and fluid leakage into tissues.
- This causes edema (swelling) in the legs due to increased hydrostatic pressure.
Why A is correct:
- Leg muscle contractions act as a "peripheral pump" to propel venous blood against gravity, per circulatory physiology; fewer contractions impair this mechanism, causing blood pooling and swelling.
Why the others are wrong:
- B: Heart rate remains normal or elevates slightly in flight due to stress, not reduced from lack of exercise.
- C: Arterial pressure is unchanged and sufficient to deliver blood; the issue is venous return, not arterial force.
- D: Vein valves function normally but cannot compensate without muscle action to fill and propel blood forward.
Final answer: A
Topic: Circulatory system
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