O Levels Biology (5090)•5090/11/O/N/24

Explanation
Optimal pH for stomach protease activity
Steps:
- Stomach proteases like pepsin function in acidic conditions of the stomach.
- Pepsin's activity peaks at low pH (around 2) due to the stomach's HCl environment.
- Examine diagrams for enzyme activity versus pH, identifying the curve with maximum rate at acidic pH.
- Match the diagram showing highest activity below pH 3 and low activity at neutral or basic pH.
Why C is correct:
- Diagram C displays peak activity at pH 2, aligning with pepsin's optimal function in acidic gastric conditions as defined by enzyme-substrate interactions stabilized at low pH.
Why the others are wrong:
- A shows peak at pH 7, typical for neutral pH enzymes like pancreatic proteases.
- B shows peak at pH 9, suited for alkaline environments, not stomach.
- D shows flat or broad activity across pH, ignoring pH specificity of pepsin.
Final answer: C
Topic: Effects of temperature and pH
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