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O Levels Biology (5090)•5090/11/O/N/22
Question 37 from 5090/11/O/N/22

Explanation

Conditional Probability in Lethal Allele Inheritance

Steps:

  • Cross two heterozygotes (Ss × Ss): offspring ratios are ¼ SS (thick), ½ Ss (thin), ¼ ss (non-surviving).
  • Surviving offspring total ¾ (SS + Ss).
  • Heterozygotes (Ss) among survivors: (½) / (¾) = ⅔.
  • Thus, probability a surviving snail is heterozygous is 0.67.

Why D is correct:

  • In lethal recessive inheritance, the conditional probability formula—P(heterozygote | survival) = P(heterozygote and survival) / P(survival)—yields ⅔ for Ss among viable offspring.

Why the others are wrong:

  • A: Incorrect, as heterozygotes survive (ss is lethal).
  • B: Matches frequency of SS overall, not conditional on survival.
  • C: Matches unconditional heterozygote frequency (½), ignoring lethality.

Final answer: D

Topic: Inheritance

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