O Levels Biology (5090)•5090/11/O/N/22

Explanation
Conditional Probability in Lethal Allele Inheritance
Steps:
- Cross two heterozygotes (Ss × Ss): offspring ratios are ¼ SS (thick), ½ Ss (thin), ¼ ss (non-surviving).
- Surviving offspring total ¾ (SS + Ss).
- Heterozygotes (Ss) among survivors: (½) / (¾) = ⅔.
- Thus, probability a surviving snail is heterozygous is 0.67.
Why D is correct:
- In lethal recessive inheritance, the conditional probability formula—P(heterozygote | survival) = P(heterozygote and survival) / P(survival)—yields ⅔ for Ss among viable offspring.
Why the others are wrong:
- A: Incorrect, as heterozygotes survive (ss is lethal).
- B: Matches frequency of SS overall, not conditional on survival.
- C: Matches unconditional heterozygote frequency (½), ignoring lethality.
Final answer: D
Topic: Inheritance
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