O Levels Biology (5090)•5090/11/O/N/20

Explanation
Blood Clotting Cascade Steps:
- Identify key players: Platelets initiate clotting by aggregating at injury site.
- Recall conversion: Clotting factors, aided by platelets, turn soluble fibrinogen into insoluble fibrin.
- Form clot: Fibrin strands trap blood cells to stabilize the clot.
- Match options: Only A fits the sequence of initiator, precursor, and product.
Why A is correct:
- Platelets release chemicals and provide surface for enzymes to convert fibrinogen (soluble protein) to fibrin (insoluble mesh) per hemostasis mechanism.
Why the others are wrong:
- B: Red blood cells transport oxygen but do not convert fibrinogen to fibrin.
- C: Reverses fibrin and fibrinogen; red blood cells play no conversion role.
- D: Reverses fibrin and fibrinogen; platelets convert fibrinogen to fibrin, not vice versa.
Final answer: A
Topic: Blood
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