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O Levels Biology (5090)•5090/12/O/N/19
Question 39 from 5090/12/O/N/19

Explanation

X-linked recessive inheritance probability for male offspring

Steps:

  • Night-blindness is X-linked recessive; males express the trait if they inherit the allele from carrier mother.
  • Probability unborn child is male: 1/2.
  • If male, probability of inheriting recessive allele from heterozygous mother: 1/2 (mother passes X with allele half the time).
  • If mother’s carrier status is uncertain (e.g., 1/2 chance based on pedigree), multiply by 1/2: overall 1/2 × 1/2 × 1/2 = 1/8.

Why C is correct:

  • 1/8 matches the product of independent probabilities: sex (1/2), maternal carrier status (1/2), and allele transmission (1/2) per Mendel's law of segregation.

Why the others are wrong:

  • A: Ignores genotype probability, assumes only 1/2 male chance.
  • B: Assumes certain carrier mother, omitting status uncertainty (1/2 × 1/2 = 1/4).
  • D: Overestimates by including female carriers or unaffected outcomes.

Final answer: C

Topic: Inheritance

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