O Levels Biology (5090)•5090/11/M/J/24

Explanation
Adrenaline stimulates glycogen breakdown in liver cells
Steps:
- Adrenaline binds to liver cell receptors, activating the fight-or-flight response.
- This triggers cAMP production, which activates protein kinase A.
- Protein kinase A phosphorylates glycogen phosphorylase, initiating glycogenolysis.
- Glycogen breaks down to glucose-1-phosphate, converted to glucose for blood release.
Why A is correct:
- Adrenaline promotes glycogenolysis via the hormonal control pathway, raising blood glucose for energy during stress, as defined in endocrine physiology.
Why the others are wrong:
- B: Urea formation is stimulated by glucagon or high-protein diets, not adrenaline.
- C: Protein breakdown is cortisol-driven, not adrenaline's primary liver effect.
- D: Glucose-to-glycogen conversion (glycogenesis) is insulin-stimulated, opposing adrenaline's action.
Final answer: A
Topic: Blood glucose control
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