O Levels Biology (5090)•5090/11/M/J/23

Explanation
HIV Weakens Immunity by Depleting Lymphocytes
Steps:
- HIV primarily infects and destroys CD4+ T lymphocytes, key immune cells.
- This depletion reduces the overall number of lymphocytes.
- Fewer helper T cells impair coordination of immune responses, weakening the system.
- Antibody production decreases due to lack of T cell support for B cells.
Why A is correct:
- HIV targets CD4+ T cells, causing their progressive destruction, which directly weakens the immune system and reduces antibody production as per immunological definitions of AIDS progression.
Why the others are wrong:
- B: HIV does not strengthen the immune system; it weakens it.
- C: Immune system weakens, not strengthens, despite the repeated phrasing.
- D: HIV weakens immunity and decreases, not increases, antibody production.
Final answer: A
Topic: Immunity
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