O Levels Biology (5090)•5090/12/M/J/21

Explanation
Enzyme Denaturation by High Temperature
Steps:
- Enzymes are proteins that function via a specific active site shape.
- High temperature breaks weak bonds like hydrogen bonds in the protein.
- This alters the tertiary structure, changing the active site's shape.
- The process that describes this change is denaturation.
Why A is correct:
- Denaturation specifically refers to the unfolding or structural change in proteins, including enzymes, caused by heat, which deforms the active site and impairs function (per protein biochemistry definitions).
Why the others are wrong:
- B: Destroyed suggests total elimination or breakdown, not reversible shape alteration.
- C: Deleted implies removal or excision, unrelated to temperature effects on structure.
- D: Distorted is a general term for shape change but lacks the precise biochemical meaning of denaturation.
Final answer: A
Topic: Effects of temperature and pH
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