O Levels Biology (5090)•5090/12/M/J/20

Explanation
Tobacco smoke components impairing fetal oxygen supply
Steps:
- Smoking reduces fetal oxygen by affecting maternal blood and placental flow.
- Carbon monoxide binds to hemoglobin, forming carboxyhemoglobin that carries less oxygen.
- Nicotine constricts blood vessels, limiting placental blood flow and oxygen delivery.
- Tar deposits in lungs but does not directly impact oxygen transport or flow.
Why A is correct:
- Carbon monoxide reduces oxygen-carrying capacity of blood (binds hemoglobin 200 times more tightly than oxygen); nicotine causes vasoconstriction, decreasing placental perfusion.
Why the others are wrong:
- B: Tar clogs lungs long-term but does not reduce oxygen supply acutely.
- C: Tar lacks direct role in oxygen reduction, unlike carbon monoxide alone.
- D: Tar irrelevant to oxygen; nicotine alone insufficient without carbon monoxide's binding effect.
Final answer: A
Topic: Blood
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