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O Levels Biology (5090)•5090/12/M/J/19
Question 22 from 5090/12/M/J/19

Explanation

Urea Formation in the Liver from Amino Acids

Steps:

  • Amino acids are deaminated, releasing ammonia as a toxic byproduct.
  • The liver's urea cycle converts ammonia into non-toxic urea.
  • Urea is then transported to the kidneys for excretion in urine.
  • Carbohydrates provide energy but do not contribute to urea synthesis.

Why B is correct:

  • The urea cycle, discovered by Hans Krebs, occurs exclusively in liver hepatocytes to detoxify ammonia from amino acid catabolism.

Why the others are wrong:

  • A: Kidneys filter and excrete urea but do not synthesize it.
  • C: Carbohydrates are broken down for glucose, unrelated to nitrogen waste like urea.
  • D: Liver processes carbohydrates for energy, not urea formation.

Final answer: B

Topic: Excretion

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